SDS
小鼠突触核蛋白α(SNCa)酶联免疫吸附试剂盒
Catalog #: E03S0033
Sample Type: Biological samples

 

Other Names

Mouse Alpha Synuclein ELISA kit

SNCA; NACP; PARK 1; PARK 4; PARK1; PARK4; Alpha synuclein; Alpha-Synuclein; Alpha-synuclein, isoform NACP140; alpha SYN

Research Area

Neuroscience 

Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.