SDS
小鼠糖皮质激素受体(GR)酶联免疫吸附试剂盒
Catalog #: E03G0238
Sample Type: Biological samples

 

Other Names

Mouse Glutathione Reductase ELISA kit

GSR; GLUR; GRD1; Glutathione reductase, mitochondrial

Research Area

Signal transduction, Cell Biology, Metabolism, Cancer

Background

Glutathione reductase (GR) is a member of pyridine nucleotide- disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG). In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.