SDS
人促生长激素释放激素(GHRH)酶联免疫吸附试剂盒
Catalog #: E01G0011
Sample Type: Biological samples

 

Other Names

Human Growth hormone releasing hormone ELISA kit

GRF; GHRF; GHRH; Somatoliberin precursor; Somatocrinin; Sermorelin; Growth hormone releasing hormone

Research Area

Signal transduction

Background

GHRF encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.