Other Names

Human Collagen Type X ELISA kit

Collagen type X; Col10a 1; Collagen alpha 1(X) chain; Collagen type X alpha 1 (Schmid metaphyseal chondrodysplasia); Collagen type X alpha 1; Collagen X alpha 1 polypeptide; CollagenX; Procollagen type X alpha 1; Schmid metaphyseal chondrodysplasia; Collagen alpha-1(X) chain; collagen alpha-1(X) chain precursor; Schmid metaphyseal chondrodysplasia; collagen X, alpha-1 polypeptide

Research Area

Signal transduction

Background

This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).