SDS
Sheep Osteocalcin ELISA kit
Catalog #: E14O0001
Sample Type: Biological samples

 

Other Names

BGLAP; OT; BGP; Bone Gla Protein; Bone Gamma-Carboxyglutamate Protein; Gamma-carboxyglutamic acid-containing protein

Research Area

Signal transduction, Stem cells

Background

Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein; made by osteoblasts; and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17; 21 and 24; giving it a high affinity for calcium. It also binds strongly to apatite.