SDS
大鼠窖蛋白(CAV1)酶联免疫吸附试剂盒
Catalog #: E02C0700
Sample Type: Biological samples

 

Other Names

Rat Caveolin-1 ELISA Kit

VIP21; Caveolae Protein 22kDa

Research Area

Tags & Cell Markers, Cardiovascular, Signal transduction, Cancer, Metabolism 

Background

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.