SDS
大鼠8-羟基脱氧鸟苷(8-OHdG)酶联免疫吸附试剂盒
Catalog #: E02H0007
Sample Type: Biological samples

 

Other Names

Rat 8 Hydroxy 2 desoxyguanosine ELISA kit

8 OHdG; 8OHdG; 7,8-Dihydro-8-Oxo-2'-Deoxyguanosine; 7,8-Dihydro-8-Oxodeoxyguanosine; 8-Hydroxy-2'-Deoxyguanosine; 8-Oxo-DG

Research Area

Cell Biology, Kits/Lysates/Other, Epigenetics and Nuclear Signaling

Background

8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.