SDS
大鼠醛脱氢酶3家族成员A1(ALDH3A1)酶联免疫吸附试剂盒
Catalog #: E02A1034
Sample Type: Biological samples

 

Other Names

Rat Aldehyde dehydrogenase, dimeric NADP preferring ELISA kit

ALDH3A1; ALDH3; ALDHIII; Aldehyde Dehydrogenase,Dimeric NADP-Preferring; Aldehyde dehydrogenase 3

Research Area

Signal transduction, Metabolism, Cell Biology, Neuroscience

Background

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the 代谢 of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.